The European enforcement agency's report stated some 380 matches were under investigation, including one 2009 Champions League game in England between Liverpool and Hungarian club Debrecen.
While there has never been any suspicion of wrongdoing by anyone at Liverpool, who won the match in question 1-0, Wenger feels the whole situation must act as a wake-up call to the English game. "It was absolutely a surprise (to hear) the number of games that have been fixed. For me, it is a real tsunami and a real shock," the Arsenal manager said.
"I cannot accept it. I always was a believer that there is a lot of cheating going on in our game and that we are not strong enough with what happens, nor with the doping, nor with the corruption of the referees, nor with the match-fixing.
"It is time that we tackle this problem in a very serious way and that people who cheat are punished in a very severe way as well. Sport is full of legends who are in fact cheats. We had a recent example again (in cyclist Lance Armstrong) and we all have that responsibility to fight against that."
Wenger feels the concept of fixing a result goes against the very essence of sport.
"You cannot accept when somebody who works the whole week and decides to spend his money to go to a game, that you then cheat him because everything is decided before he gets to the stadium," the Frenchman added. "I cannot stand up for that. We cannot accept that."
The Gunners boss, however, does not feel England has cause for major concern at the moment.
"I don't think at all it is a problem in the English game, and that is why it is maybe a shock for us," he said. "We are convinced we live in a world in England where although it is not a perfect world, I don't think cheating or match-fixing is a problem. In fairness I give you some credit for that because the English media would be very harsh against that."
Wenger added: "I personally feel English football is clean of cheating 100 per cent. I don't think referees are corrupt. It happened in Europe before, that is my belief, where referees were not always fair, there is history, especially in some countries, but you always have to be cautious, have your own beliefs, prove it, and that becomes more difficult."